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Buy Generic Hydrochlorothiazide

Drug Name: Generic

Category: Blood
Contents: Hydrochlorothiazide

Hydrochlorothiazide Drug Information

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Hydrochlorothiazide and its Uses

Generic Hydrochlorothiazide is a type of medicine called a thiazide diuretic. Diuretics increase the amount of urine passed, which causes the body to lose water and salt. Hydrochlorothiazide helps to treat high blood pressure (hypertension).

Generic Hydrochlorothiazide also reduces the swelling and water retention caused by various medical conditions, such as heart, liver, or kidney disease.

Generic Hydrochlorothiazide works by blocking salt and fluid reabsorption in the kidneys, causing increased urine output (diuresis).

Generic Hydrochlorothiazide has also been used in treating mild high blood pressure.

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Hydrochlorothiazide Mechanism Hctz Working

Generic Hydrochlorothiazide works by causing the kidneys to increase the amount of salts, such as potassium and sodium, which are filtered out of the blood and into the urine. When these salts are filtered out of the blood by the kidneys, water is also drawn alongside. As hydrochlorothiazide increases the removal of salts from the blood, it also causes more water to be drawn out of the blood and into the urine.

Removing water from the blood decreases the volume of fluid circulating through the blood vessels, which decreases the pressure within the blood vessels. Generic Hydrochlorothiazide therefore lowers blood pressure.

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Hydrochlorothiazide Dosage

Missed Dose of Hydrochlorothiazide

Take the missed dose of Hydrochlorothiazide as soon as you remember. However, if it is almost time for your next dose, skip the dose of Hydrochlorothiazide you missed and take only your next regularly scheduled dose. Do not take a double dose of Hydrochlorothiazide.

Excess Dose of Hydrochlorothiazide

Generic Hydrochlorothiazide in excess dose may show symptoms such as increased urination, nausea, vomiting, diarrhea, fatigue, lethargy, and unconsciousness.

Conditions for Storage of Hydrochlorothiazide

Store Hydrochlorothiazide at room temperature away from moisture and heat.

Potencies of Hydrochlorothiazide

Hydrochlorothiazide Tablets

hydrochlorothiazide 12.5 mg, & hydrochlorothiazide 25 mg.

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Food and Drug Interactions with Hydrochlorothiazide

  • Generic Hydrochlorothiazide may interact with the following medicines:
    • lithium (Lithobid, Eskalith, others)
    • digoxin (Lanoxin, Lanoxicaps
    • the cholesterol-lowering drugs cholestyramine (Questran) or colestipol (Colestid)
    • A nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin, Advil, Nuprin), naproxen (Naprosyn, Anaprox, Aleve), ketoprofen (Orudis, Orudis KT, Oruvail), indomethacin (Indocin), diclofenac (Cataflam, Voltaren), etodolac (Lodine), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), tolmetin (Tolectin), fenoprofen (Nalfon), or flurbiprofen (Ansaid)
    • A diabetes medication such as glipizide (Glucotrol), glyburide (Micronase, Glynase, Diabeta), chlorpropamide (Diabinese), tolazamide (Tolinase), tolbutamide (Orinase), and others
    • A steroid medicine such as cortisone (Cortone), dexamethasone (Decadron, Hexadrol), hydrocortisone (Cortef, Hydrocortone), prednisone (Orasone, Deltasone), prednisolone (Delta Cortef, Prelone), methylprednisolone (Medrol), and others
  • Hydrochlorothiazide may increase the effects of other drugs that cause drowsiness, including sedatives (used to treat insomnia), pain relievers, seizure medicines, antidepressants, alcohol, antihistamines, anxiety medicines, and muscle relaxants.

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Contraindications with Hydrochlorothiazide

Generic Hydrochlorothiazide may interact with the following

  • Anuria
  • Hypersensitivity to hydrochlorothiazide or to other sulfonamide-derived drugs
  • Patients with Addison's disease
  • Patients with pre-existing hypercalcaemia

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Precautions with Hydrochlorothiazide

Generic Hydrochlorothiazide should be used with caution in

  • Patients with impaired hepatic function since they may increase the risk of hepatic encephalopathy.
  • Patients with hepatic cirrhosis are particularly at risk from hypokalaemia.
  • Renal function impairment since they can further reduce renal function.
  • Hydrochlorothiazide may precipitate attacks of gout in susceptible patients.
  • Hydrochlorothiazide may cause hyperglycaemia and aggravate or unmask diabetes mellitus.
Blood-glucose concentrations should be monitored in patients taking antidiabetic agents, since requirements may change. All patients should be carefully observed for signs of fluid and electrolyte imbalance, especially in the presence of vomiting or during parenteral fluid therapy. Hydrochlorothiazide can reduce urinary excretion of calcium, sometimes resulting in mild hypercalcaemia. Elderly patients are particularly susceptible to electrolyte imbalance. There is a possibility that hydrochlorothiazide may exacerbate or activate systemic lupus erythematosus in susceptible patients.

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Adverse effects with Hydrochlorothiazide

The adverse effects associated with Hydrochlorothiazide are

  • An allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives)
  • unusual fatigue
  • abnormal bleeding or bruising
  • yellow skin or eyes
  • confusion
  • irregular heartbeats or a fluttering feeling in the chest
  • little or no urine

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