Nexium and its Uses
Generic Nexium is a proton pump inhibitor (PPI). Generic Nexium helps to treat conditions such as stomach ulcers and gastroesophageal reflux disease (GERD) by reducing the amount of acid the stomach produces.
Generic Nexium may be used in combination with two antibiotics to treat Helicobacter pylori (H. pylori) infection and duodenal ulcers.
Generic Nexium can also be used to prevent and treat peptic ulcers that can occur as a side effect of non-steroidal anti-inflammatory drugs (NSAIDs), such as diclofenac, often used to treat arthritis.
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Proton pumps are found on cells that line the stomach and are used by these cells to produce stomach acid. Esomeprazole works by inhibiting the action of the proton pumps, and this reduces the production of stomach acid.
Acid is produced in the stomach as a normal part of the digestive process. However, in the condition known as gastro-oesophageal reflux disease or acid reflux, this acid is allowed to flow back into the food pipe (oesophagus), where it causes pain and a burning sensation known as heartburn. The acid can also irritate and cause inflammation of the lining of the food pipe (reflux oesophagitis).
Generic Nexium reduces the production of stomach acid and thus reduces acid flowing back into the food pipe. It is used to relieve the symptoms of gastro-oesophageal reflux disease, such as heartburn. It is also used to treat reflux oesophagitis, because stopping the acid flowing back into the food pipe allows the lining of the food pipe to heal. Generic Nexium is also used for the long-term management of people with healed oesophagitis, as suppressing the production of stomach acid helps prevent this condition recurring.
Generic Nexium is also used to treat ulcers in the stomach or upper intestine (peptic ulcers) that are associated with a type of bacteria called Helicobacter pylori. This type of bacteria is the most common cause of peptic ulcers. The bacteria cause the stomach to produce too much acid, which irritates the lining of the stomach and upper intestine and causes ulcers.
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Nexium Dosage
Missed Dose of Nexium
Take the missed dose of Nexium as soon as you remember. However, if it is almost time for your next dose of Nexium, skip the missed dose of Nexium and take only your next regularly scheduled dose. Do not take a double dose of Nexium.
Excess Dose of Nexium
Generic Nexium in excess dose may show symptoms such as drowsiness, shortness of breath, tremor, loss of coordination, and seizures.
Conditions for Storage of Generic Nexium
Store Generic Nexium at room temperature away from moisture and heat.
Potencies of Generic Nexium
Nexium Tablets Nexium 20 mg & Nexium 40 mg
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Food and Drug Interactions with Nexium
- Generic Nexium may increase the blood level of the following medicines:
- barbiturates
- citalopram
- clomipramine
- diazepam
- imipramine
- phenytoin (the manufacturer recommends that people taking phenytoin should have their phenytoin blood level monitored when starting or stopping esomerazole)
- proguanil
- propranolol
- Generic Nexium may increase the anti-blood-clotting effect of the anticoagulant medicine warfarin. If you are taking warfarin it is recommended that your blood clotting time (INR) is monitored after starting and stopping Generic Nexium.
- Generic Nexium may decrease the absorption of the following medicines from the gut, and thus may make them less effective:
- itraconazole
- ketoconazole
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Contraindications with Nexium
Generic Nexium is contraindicated in the following
- Children
- Pregnancy & Breastfeeding
- Inherited deficiency of sucrase and isomaltase in the gut, leading to intolerance to sugars in the diet
- Inherited inability to absorb the sugars glucose and galactose (glucose-galactose malabsorption)
- Inherited intolerance to fructose in the diet
- Allergy to one or any of its ingredients
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Precautions with Nexium
Generic Nexium should be used with caution in severely decreased kidney & liver function.
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Adverse effects with Nexium
The adverse effects associated with Generic Nexium are
- Headache
- Disturbances of the gut such as diarrhea, constipation, nausea, vomiting or abdominal pain
- Excess gas in the stomach and intestines (flatulence)
- Dry mouth
- Skin reactions such as rash and itch
- Inflammation of the skin (dermatitis)
- Dizziness
- Pain in the muscles and joints
- Swelling of the legs and ankles due to excess fluid retention (peripheral oedema)
- Pins and needles (paraesthesia)
- Depression
- Agitation
- Confusion
- Difficulty sleeping (insomnia)
- Sleepiness (somnolence)
- Liver or blood disorders
- Taste disturbance
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