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Buy Generic Toprol XL

Drug Name: Generic Toprol XL

Category: Blood Pressure Contents: Metoprolol XR

Toprol XL Drug Information

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Toprol XL and its Uses

Generic Toprol XL is in a class of medications called beta blockers.

Generic Toprol XL is used alone or in combination with other medications to treat high blood pressure. Toprol XL also is used to prevent angina (chest pain) and to treat heart attacks.

Generic Toprol XL is in a class of medications called beta blockers. Toprol XL works by slowing the heart rate and relaxing the blood vessels so the heart does not have to pump as hard.

Generic Toprol XL is a beta blocker which is sometimes effective in the prevention of migraine. It is a cardio-selective beta blocker which can be used for some patients who have co-existing asthma.

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Toprol XL Mechanism Toprol XL Working

Toprol XL blocks beta receptors in the heart, lungs and other organs of the body. Blocking these receptors prevents the action of two chemicals called noradrenaline and adrenaline that occur naturally in the body. These are often referred to as the 'fight or flight' chemicals as they are responsible for the body's reaction to stressful situations.

Blocking the beta receptors in the heart causes the heart to beat more slowly and with less force. The heart therefore uses less energy and the pain of angina is prevented. Abnormal heart rhythms are also prevented.

Due to the heart beating more slowly and with less force, the pressure at which blood is pumped out of the heart to the rest of the body is reduced. This is just one of the ways in which Generic Toprol XL helps to reduce blood pressure, however the whole mechanism is not fully understood.

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Toprol XL Dosage

Missed Dose

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of Toprol XL.

Excess Dose of Toprol XL

Toprol XL in excess dose may show symptoms such as slow heart beat, shortness of breath, fainting, dizziness, weakness, confusion, nausea, and vomiting.

Conditions for Storage of Toprol XL

Store Toprol XL at room temperature away from moisture and heat.

Potencies of Toprol XL

Toprol XL Tablets

Toprol xl 50 mg & Toprol xl 100 mg.

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Food and Drug Interactions with Toprol XL

  • When taken with other medicines that decrease blood pressure there is an increased risk of a large drop in blood pressure.
  • There may be an increased risk of slow heart rate when Toprol XL is taken with digoxin.
  • In diabetic people, Toprol XL can prolong the lowering of blood sugar (hypoglycaemia) caused by insulin or other antidiabetic medicines. Individuals should monitor their blood sugar, as Toprol XL can also mask the signs of hypoglycaemia.
  • When Toprol XL is taken with calcium channel blockers such as verapamil, the risk of slow heart rate, hypotension and heart failure may be increased. Verapamil should be avoided with Toprol XL.
  • If Generic Toprol XL is taken together with clonidine, there is a risk of a rebound increase in blood pressure if clonidine is stopped. Generic Toprol XL should be stopped several days before slowly stopping the clonidine.
  • Non-steroidal anti-inflammatory drugs (NSAIDs) such as indomethacin may reduce the antihypertensive effects of Toprol XL.
  • Care should be taken when adrenaline is given with Generic Toprol XL as this combination can cause severely high blood pressure and slow heart rate.
  • Rifampicin increases the removal of Toprol XL from the body.
  • The use of certain anaesthetics with Toprol XL may increase the risk of low blood pressure and slow heart rate.
  • When lignocaine is taken together with Generic Toprol XL the blood level of lignocaine may be increased.
  • Anti-arrhythmic medicines such as amiodarone or dipyridamole may increase the risk of slow heart rate when taken with Toprol XL.

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Contraindications with Toprol XL

Toprol XL is contraindicated in the following

  • A problem common in the elderly, related to poor control of the working of the heart (sick sinus syndrome)
  • Allergy to beta-blockers
  • Angina not well controlled by medical treatment (unstable angina)
  • Blockage of arteries in the extremities (peripheral arterial occlusion)
  • Defect of the heart's electrical message pathways resulting in decreased function of the heart (heart block)
  • Failure of the heart to maintain adequate circulation of blood (cardiogenic shock)
  • Heart failure
  • Increased acid levels in the blood (metabolic acidosis)
  • Low blood pressure (hypotension)
  • Tumour of the adrenal gland (phaeochromocytoma)
  • Very slow heart rate (severe bradycardia)
  • Allergy to one or any of its ingredients
  • Pregnancy & Breastfeeding

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Precautions with Toprol XL

Toprol XL should be used with caution in

  • Abnormal muscle weakness (myasthenia gravis)
  • Defect of the heart's electrical message pathways resulting in decreased function of the heart (heart block)
  • Diabetes
  • Elderly people
  • History of allergies
  • History of asthma or wheezing
  • Kidney disease
  • Liver disease
  • Pre-surgical management of adrenal gland tumours (phaeochromocytoma), but only in combination with an alpha blocking medicine
  • Psoriasis

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Adverse effects with Toprol XL

The adverse effects associated with Toprol XL are

  • Slower than normal heart beat (bradycardia)
  • Inability of the heart to pump blood efficiently (heart failure)
  • Disturbed sleep
  • Fatigue
  • Disturbances of the gut such as diarrhoea, constipation, nausea, vomiting or abdominal pain
  • Dizziness
  • Breathing difficulties due to a narrowing of the airways (bronchospasm)
  • Cold extremities, eg hands and feet
  • Rash

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