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I. Effexor XR Fact File

Effexor XR medication was first introduced by Wyeth Pharmaceuticals.

, a subsidiary of (formerly American Home Products), makes pharmaceuticals to treat cardiovascular, gastrointestinal, and infectious diseases, as well as cancer, women's health concerns, depression, vaccines and infectious disease hemophilia, immunology, and oncology. Wyeth is also a leader in the development of nutritionals.

is a global leader in pharmaceuticals, consumer health care products, and animal health care products. With research and development (R&D) programs focused on small molecules, vaccines, and biotechnology, is exploring more than 60 new therapies for medical conditions such as diabetes, breast cancer, multiple sclerosis, HIV, Alzheimer's disease, and schizophrenia.

is a leader in women's health care with postmenopausal hormone therapy products for women, as well as hormone-based oral contraceptive products.

best selling drugs include antidepressant Effexor, estrogen replacement therapy Premarin, and acid reflux disease drug Protonix. The company also makes vaccines and a line of nutritional products, including infant formulas and adult supplements.

II. Effexor XR Medication

Generic Effexor XR is a prescription medication used to treat depression, generalized anxiety disorder, and social anxiety disorder, but is also used to treat obsessive-compulsive disorder (OCD) or Fibromyalgia.

Effexor XR medication is known as an SNRI (serotonin and norepinephrine reuptake inhibitor) and is believed to help treat depression and the associated symptoms of anxiety by affecting the level of two chemicals in the brain-serotonin and norepinephrine. These two chemicals are thought to play a key role in depression and the associated symptoms of anxiety. Correcting the imbalance of these two chemicals may help relieve depression symptoms and the associated symptoms of anxiety-which can be a positive step toward getting your life back.

Effexor XR medication has also been proven to keep depression from coming back. Over a 52-week period, a large majority of patients in studies did not see their symptoms return.

Antidepressants: Information on Effexor XR

Antidepressants are medication that relieve the symptoms of depression. They were first developed in the 1950s and have been used regularly since then. There are almost thirty different kinds of antidepressants medication available today and there are three main types:

  • Tricyclics
  • MAOIs (Monoamine oxidase inhibitors)
  • SSRIs (Selective Serotonin Reuptake Inhibitors)
  • SNRIs (Serotonin and Noradrenaline Reuptake Inhibitors)

Antidepressants medication work by altering the way in which certain chemicals work in our brains. These chemicals are made by our body and are called neuro-transmitters. They pass signals from one brain cell to another.

In depression, some of the neurotransmitter systems, particularly those of Serotonin and Noradrenaline, do not seem to be working properly. We think that antidepressants work by increasing the activity of these chemicals in our brains.

After 3 months of regular treatment, the proportions of people with depression who will be much improved are 50% and 65% if given an antidepressant compared with 25 - 30% if given an inactive "dummy" pill, or placebo.

The older medication (Tricyclics) are just as effective as the newer ones (SSRIs) but, on the whole, the newer ones seem to have fewer side-effects. A major advantage for the newer medication is that they are not so dangerous if someone takes an overdose.

Depression: Information

Some Clinical depression is a common, yet serious, illness that affects more than 19 million Americans each year.

Unfortunately, only one-third of sufferers seeks treatment even though the illness can be effectively treated in 80 percent of all cases. Although depression is a real medical illness, many people still mistakenly believe it is a personal weakness.

Symptoms of Depression

The symptoms of clinical depression can vary from person to person. The symptoms can range from mild to severe and the causes of depression can often be complex.

If you have been experiencing five (5) or more of the Given below symptoms for more than two (2) weeks, if suicide is a serious concern, or if the symptoms are severe enough to interfere with a daily routine -- see your doctor or qualified mental health professional.

  • Persistent sad, anxious or "empty" mood
  • Sleeping too much or too little; middle-of-night or early-morning waking
  • Reduced appetite and weight loss, or increased appetite and weight gain
  • Loss of pleasure and interest in activities once enjoyed, including sex
  • Irritability, restlessness
  • Persistent physical symptoms that do not respond to treatment (such as chronic pain or digestive disorders)
  • Difficulty concentrating, remembering or making decisions
  • Fatigue or loss of energy
  • Feeling guilty, hopeless or worthless
  • Thoughts of death or suicide

Causes of Depression

For some people, a combination of many factors may be causing clinical depression. For others, a single factor may be triggering the illness. Depression often is related to the following.

  • Imbalance of brain chemicals called neurotransmitters - Changes in these brain chemicals may cause or contribute to clinical depression.
  • Certain diseases or illnesses - Ailments such as cancer, heart disease, Parkinson's disease, Alzheimer's disease, diabetes and hormonal disorders can often trigger clinical depression. This is referred to as co-occurring depression.
  • Negative thinking patterns - People who are pessimistic, have low self-esteem, worry excessively, or feel they have little control over life events are more likely to develop clinical depression.
  • Family history of depression - A genetic history of clinical depression can increase one's risk for developing the illness. But depression also occurs in people who have had no family members with depression.
  • Difficult life events - Events such as the death of a loved one, divorce, financial strains, history of trauma, moving to a new location or significant loss can contribute to the onset of clinical depression.
  • Certain medications - Some medication can actually cause clinical depression. Therefore, it is important that people inform their doctors of all medications they are taking and report any depressive symptoms.
  • Frequent and excessive alcohol consumption - Drinking large amounts of alcohol on a regular basis can sometimes lead to clinical depression. Excessive alcohol consumption is also sometimes a symptom of depression.

Side effects of Antidepressants


These commonly cause a dry mouth, a slight tremor, fast heartbeat, constipation, sleepiness, and weight gain.

Particularly in some older people, they may cause confusion, slowness in starting and stopping when passing water, faintness through low blood pressure, and falls. If you have heart trouble, it may be best not to take one of this group of antidepressants. Men may experience difficulty in getting or keeping an erection, or delayed ejaculation. Tricyclic antidepressants are dangerous in overdose.


During the first couple of weeks of taking them, you may feel sick and more anxious. Some of these medication can produce nasty indigestion, but you can usually stop this by taking them with food. More seriously, they may interfere with your sexual function. There have been reports of episodes of aggression, although these are rare.

Some people get a small number of mild side-effects (if any). The side effects usually wear off over a couple of weeks as your body gets used to the medication. It is important to have this whole list, though, so you can recognise side effects if they happen. You can then talk them over with your doctor.

some of the more serious side effects are problems with urinating, difficulty in remembering, falls, confusion - are uncommon in healthy, younger or middle-aged people. It is common, if you are depressed, to think of harming or killing yourself. Tell your doctor - suicidal thoughts will pass once the depression starts to lift.


The side effects are very similar to the SSRIs, but, Generic Effexor (Venlafaxine) is not recommended for people who have heart problems, high blood pressure or problems with the salt levels in their blood. They can be helpful if other antidepressants have failed but they should only be prescribed by doctors with special experience in mental health.


MAOIs type of antidepressant is rarely prescribed these days. MAOIs can give you a dangerously high blood pressure if you eat foods containing a substance called Tyramine. If you agree to take an MAOI antidepressant your doctor will give you a list of foods to avoid.

Uses of Antidepressants

  • Moderate to severe depressive illness (Not mild depression)
  • Severe anxiety and panic attacks
  • Obsessive compulsive disorders
  • Chronic pain
  • Eating disorders
  • Post-traumatic stress disorder

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